PDRN vs. Polynucleotides vs. Peptides: What's the Difference?
Three 'skin booster' ingredients that sound alike. Here is how PDRN, polynucleotides (PN) and peptides differ.
PDRN
Short DNA fragments purified mostly from salmon. Popular in Korean clinics and serums.
Polynucleotides (PN)
Longer DNA chains from the same sources. Mainly used in clinic injectables; some topical products exist.
Peptides
Short chains of amino acids, unrelated to DNA. Common in anti-aging creams.
Which to choose
For a gentle at-home serum, PDRN is the most common Korean pick. Peptide creams are a good partner at night.
Frequently asked questions
Is PN stronger than PDRN?
They are used differently; direct comparisons in topical products are limited.
Can I combine PDRN and peptides?
Yes.
This article is for general information and is not medical advice. Products sold by KAREMEDI are cosmetics and are not intended to diagnose, treat, cure or prevent any disease.