PDRN Serum: What 'Salmon DNA' Skincare Actually Does
PDRN, or polydeoxyribonucleotide, went from Korean dermatology clinics to serums. Here is what it is, what the evidence says and how to use it.
What PDRN is
PDRN is a mix of DNA fragments, usually purified from salmon or trout. Korean clinics use injectable forms in skin-booster treatments; topical serums bring the ingredient into home routines.
What to expect from a topical serum
Topical PDRN serums are used to support skin that looks dull or tired and to complement post-procedure care. Results from a serum are gentler than in-clinic injections, so set expectations accordingly.
How to use it
Apply two to three drops after toner, before cream. Use once or twice daily. PDRN pairs well with centella and panthenol. Compare it with similar actives in PDRN vs polynucleotides vs peptides.
Frequently asked questions
Is PDRN vegan?
Most PDRN comes from fish. Some newer plant-derived versions exist.
Is a PDRN serum the same as a skin booster injection?
No. Injections are medical procedures; serums are cosmetics applied to the skin surface.
This article is for general information and is not medical advice. Products sold by KAREMEDI are cosmetics and are not intended to diagnose, treat, cure or prevent any disease.